The “angle” in the eye refers to the structure between the iris and the cornea, where a good portion of the eye’s aqueous fluid leaves the eye. If there is a problem with this structure, it can prevent the fluid from draining properly, causing increased eye pressure.
Normal Tension Glaucoma (Low Tension Glaucoma)
Normal or Low Tension Glaucoma occurs in the presence of normal or low eye pressure. Again, the exact cause is still up for debate, but factors like blood flow to the optic nerve may play a role. Diabetes, low blood pressure, and Obstructive sleep apnea (OSA) are all risk factors. The National Institutes of Health study of 4.5M patients, Obstructive sleep apnoea and glaucoma: a systematic review and meta-analysis states that, “patients with OSA had up to 40% higher odds of glaucoma.”
It’s believed that the optic nerve itself is weak and cannot withstand even a slightly abnormal eye pressure. Treatment still focuses on lowering eye pressure to protect the optic nerve.
Glaucoma Symptoms
Most forms of glaucoma have no early symptoms and are not painful. Vision loss is typically slow and at the edges, or periphery, of vision. It is impossible to detect without an eye exam. Some less common forms, such as acute angle-closure glaucoma, can cause sudden symptoms such as nausea, halos around lights, severe eye pain, and require urgent care.
Understanding Your Risk Profile: What are the risk factors for glaucoma?
Glaucoma risk is not uniform; it is a complex intersection of genetics, systemic health, and ocular anatomy. While anyone can develop glaucoma, clinical data show that certain populations face significantly higher risks:
- African and Hispanic Ancestry: Individuals of African and Hispanic descent are statistically more likely to develop Primary Open-Angle Glaucoma (POAG). In fact, research indicates that African Americans are 6 to 8 times more likely than Caucasians to develop glaucoma, often at an earlier age and with more rapid progression.
- Asian Ancestry: Those of Asian descent have a significantly higher predisposition for Angle-Closure Glaucoma, which can account for nearly half of all glaucoma-related blindness worldwide, despite being less common than open-angle variants.
- Northern European Ancestry: This group is specifically linked to Pseudoexfoliation Syndrome, a condition where flake-like material deposits in the eye’s drainage angle, leading to a difficult-to-treat form of high-pressure glaucoma.
Medical & Physical Predispositions
Beyond heritage, your systemic health plays a vital role in optic nerve resilience. We monitor the following “comorbidities” or the simultaneous presence of two or more diseases or medical conditions in a patient closely:
- Vascular Health: Diabetes mellitus, chronic hypertension (high blood pressure), and even hypotension (low blood pressure) can compromise blood flow to the optic nerve.
- Sleep & Neurological Factors: Obstructive sleep apnea and chronic migraines are recognized indicators of increased susceptibility.
- Ocular Anatomy: Patients with extreme myopia (nearsightedness) or hyperopia (farsightedness), as well as those with thin or “fragile” optic nerves, require more frequent screening.
Medication Risks
A critical, often overlooked factor is the prolonged use of corticosteroids (cortisone). Whether administered via eye drops, inhalers, or oral tablets, steroids can significantly increase intraocular pressure in “steroid responders.” If you are on long-term steroid therapy, specialized monitoring at Relf EyeCare is essential to prevent secondary glaucoma.
Treatment
Glaucoma is a treatable disease. Treatment always involves obtaining a lower or healthier eye pressure. This healthy pressure is different for everyone and will be determined by your eye doctor. At Relf EyeCare, our approach to initial treatment usually begins with a single eye drop once a day, and additional drops may be added as needed. Eye drops may include prostaglandin analogs, beta blockers, alpha agonists, carbonic anhydrase inhibitors, rho kinase inhibitors, nitric oxide-donating analogs, or combination drops. Each of these are prescription drops and cannot be found over-the-counter.
If eye drops aren’t effectively managing your eye pressure, we offer more permanent solutions, including laser therapy like Selective Laser Trabeculoplasty (SLT) and advanced surgical options like MIGS (Micro-Invasive Glaucoma Surgery). Our goal is always prevention; if your diagnostic testing shows you are at a significantly high risk for the disease, our doctors may recommend starting a preventative treatment plan now to protect your vision for the future.
The best way to prevent vision loss from glaucoma is early detection, consistent treatment, and follow-up, since the damage has already occurred and cannot be reversed.

Millerwoods Health Care Campus